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Evaluation of the electrochemical behavior and analytical potentialities of a carbon paste electrode modified with a ruthenium (III) piperidinedithiocarbamate complex.

Authors :
Ramos LA
Cavalheiro ET
Chierice GO
Source :
Farmaco (Societa chimica italiana : 1989) [Farmaco] 2005 Feb; Vol. 60 (2), pp. 149-55.
Publication Year :
2005

Abstract

The preparation and electrochemical characterization of a carbon paste electrode modified with bis(N,N-piperidinedithiocarbamate)-mu-tris(N,N-piperidinedithiocarbamate)diruthenium(III) complex, alpha-[Ru2(Pip)5]Cl are described. The best voltammetric response was obtained for a 10% (m/m) alpha-[Ru2(Pip)5]Cl content in the paste, potassium acid phthalate solution pH 4.0 as supporting electrolyte and scan rate of 100 mV s-1. The analytical potentialities of the electrode have been evaluated using L-ascorbic acid (vitamin C) as a probe. A sensitive linear voltammetric response for L-ascorbic acid was obtained in the concentration range 4.50-113x10(-5) mol l-1 (7.92-200 mg l-1) with a slope of 1.12x10(4) microA mol-1, and a detection limit (3sigma/slope) of 7.00x10(-6) mol l-1 using cyclic voltammetry. The concentrations of L-ascorbic acid in pharmaceutical formulations (tablets and liquid) were determined using the modified electrode and compared with an iodimetric procedure with good agreement at the 95% confidence and relative error lower than 1%.

Details

Language :
English
ISSN :
0014-827X
Volume :
60
Issue :
2
Database :
MEDLINE
Journal :
Farmaco (Societa chimica italiana : 1989)
Publication Type :
Academic Journal
Accession number :
15752473
Full Text :
https://doi.org/10.1016/j.farmac.2004.11.006