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Anemia and new-onset congestive heart failure in the general Medicare population.
- Source :
-
Journal of cardiac failure [J Card Fail] 2005 Mar; Vol. 11 (2), pp. 99-105. - Publication Year :
- 2005
-
Abstract
- Background: Anemia is associated with disease severity and prognosis for patients with congestive heart failure (CHF). It is unknown whether anemia is associated with the development of new-onset CHF in the elderly.<br />Methods and Results: This retrospective longitudinal cohort study used the Medicare 5% database. In the incident analysis, the study sample comprised subjects without CHF in 1999 (n = 1,063,495); the main exposure variable evaluated was the presence or absence of anemia in 1999; and the primary study outcome was the occurrence of new-onset CHF. The prevalence of chronic anemia and CHF in 1999 was 5.0% and 9.9%, respectively. The incidence of new-onset CHF in 2000 in those with and those without anemia in 1999 was 12.3% and 5.9%, respectively, corresponding to an adjusted hazard ratio of 1.29 ( P < .001), a value intermediate between the hazard ratios of 1.13 ( P < .001), and 1.76 ( P < .001) associated with hypertension and atherosclerotic heart disease, respectively. Anemia also was associated with death in the year after new-onset CHF (adjusted hazard ratio, 1.28; P < .001).<br />Conclusion: Anemia in the Medicare population is associated with the diagnosis and prognosis of new-onset CHF.
- Subjects :
- Age Factors
Aged
Aged, 80 and over
Anemia complications
Cohort Studies
Cross-Sectional Studies
Databases, Factual
Female
Heart Failure complications
Humans
Incidence
Longitudinal Studies
Male
Medicare statistics & numerical data
Proportional Hazards Models
Retrospective Studies
United States epidemiology
Anemia epidemiology
Heart Failure epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 1071-9164
- Volume :
- 11
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Journal of cardiac failure
- Publication Type :
- Academic Journal
- Accession number :
- 15732028
- Full Text :
- https://doi.org/10.1016/j.cardfail.2004.06.435