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[Molecular analysis for prostate cancer].
- Source :
-
Nihon rinsho. Japanese journal of clinical medicine [Nihon Rinsho] 2005 Feb; Vol. 63 (2), pp. 213-7. - Publication Year :
- 2005
-
Abstract
- The molecular and biochemical mechanisms contributing to the development and progression of prostate carcinogenesis are still unknown. Recent technologies such as, real-time PCR, microarray, and laser capture microdissection, have accelerated the study of the molecular events involved in prostate cancer. The expression and function of numerous genes have been shown to be altered in prostate cancer. Such gene regulations are involved in cell cycle, signal transduction pathways, or gene expression. Analysis of the genes during prostate cancer progression has provided a better understanding of the basis of the disease. This review summarises current knowledge of the molecular analysis for prostate cancer.
- Subjects :
- Exons genetics
Gene Expression Regulation, Neoplastic
Genes, Tumor Suppressor
Humans
Male
Microdissection
Mutation
Oligonucleotide Array Sequence Analysis
Oncogenes
Polymerase Chain Reaction
Polymorphism, Single Nucleotide
Prostatic Neoplasms pathology
Receptors, Androgen genetics
Transcriptional Activation
Trinucleotide Repeats
Prostatic Neoplasms genetics
Subjects
Details
- Language :
- Japanese
- ISSN :
- 0047-1852
- Volume :
- 63
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Nihon rinsho. Japanese journal of clinical medicine
- Publication Type :
- Academic Journal
- Accession number :
- 15714968