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Description of a technique for anaesthetizing pregnant ewes for fetal surgery.
- Source :
-
Laboratory animals [Lab Anim] 2005 Jan; Vol. 39 (1), pp. 94-9. - Publication Year :
- 2005
-
Abstract
- General anaesthesia in 12 pregnant ewes undergoing surgery for fetal physiological research was supplemented with an intravenous infusion of remifentanil. This allowed us to employ a lighter plane of surgical anaesthesia and to use intermittent positive pressure ventilation. Our aim was to improve fetomaternal outcome. We monitored maternal pulse, blood pressure, transcutaneous oxygen saturation and end-tidal carbon dioxide levels. Remifentanil doses of 0.75-2.0 microg/kg/min were needed and typically this allowed halothane concentrations of 1-1.5% to be used for maintenance of anaesthesia. Surgery lasted up to 2.5 h. All 12 ewes and their singleton fetuses survived the peri- and postoperative period in good condition.
- Subjects :
- Anesthesia, Obstetrical methods
Anesthetics, Inhalation
Anesthetics, Intravenous
Animals
Blood Gas Monitoring, Transcutaneous veterinary
Blood Pressure
Carbon Dioxide analysis
Female
Halothane administration & dosage
Oxygen blood
Piperidines administration & dosage
Pregnancy
Pulse
Remifentanil
Anesthesia, Obstetrical veterinary
Fetus surgery
Sheep embryology
Subjects
Details
- Language :
- English
- ISSN :
- 0023-6772
- Volume :
- 39
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Laboratory animals
- Publication Type :
- Academic Journal
- Accession number :
- 15703129
- Full Text :
- https://doi.org/10.1258/0023677052886600