[Study on the clinical and biological characteristics of 20 cases of chronic lymphoid leukemias].

Objective: To further define the chronic lymphoid leukemia (CLL).
Methods: Tweenty cases of CLL classified after the FAB proposals (1989) were retrospectively analyzed.
Results: Based on the clinical features, cell/tissue morphology, immunophenotype, IgH and TCR gamma gene rearrangement serum or urine immunoglobulin levels, 16 cases of B-lymphoid leukemia (12 of CLL, 1 of PLL, 2 of leukemia/lymphoma, and 1 of WM) as well as 4 cases of T-lymphoid leukemia (2 of leukemia/lymphoma, 1 of T-LGLL, and 1 of NK-LGLL) were identified. The diagnostic criteria,cell morphology,biological characteristics and prognosis for CLL were discussed.
Conclusion: T-leukemia/lymphoma should be incorporated in the classification of CLL.