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A diketopiperazine dimer from a marine-derived isolate of Aspergillus niger.

Authors :
Ovenden SP
Sberna G
Tait RM
Wildman HG
Patel R
Li B
Steffy K
Nguyen N
Meurer-Grimes BM
Source :
Journal of natural products [J Nat Prod] 2004 Dec; Vol. 67 (12), pp. 2093-5.
Publication Year :
2004

Abstract

The new diketopiperazine dimer 1, as well as the known compounds TMC-256A1 (2), TMC-256C1 (3), and demethylkotanin (4), were isolated from a culture of Aspergillus niger. The gross structure of 1 was determined by 2D NMR studies and comparison with literature data, and the absolute stereochemistry was elucidated by chiral HPLC analysis of the hydrolysis products.

Details

Language :
English
ISSN :
0163-3864
Volume :
67
Issue :
12
Database :
MEDLINE
Journal :
Journal of natural products
Publication Type :
Academic Journal
Accession number :
15620260
Full Text :
https://doi.org/10.1021/np0497494