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Coexistent thyroid pathologies and high rate of papillary cancer in patients with primary hyperparathyroidism: controversies about minimal invasive parathyroid surgery.
- Source :
-
Acta chirurgica Belgica [Acta Chir Belg] 2004 Oct; Vol. 104 (5), pp. 568-71. - Publication Year :
- 2004
-
Abstract
- Thyroid carcinoma and benign thyroid diseases associated with primary hyperparathyroidism (PHPT) may cause difficulties in the diagnosis, localization and therapy of PHPT. In this study, we analysed coexistent thyroid pathologies in 51 patients who underwent neck exploration with a diagnosis of PHPT between 1999--2002. Five hundred thirteen patients who underwent thyroidectomy for nodular thyroid disease without a parathyroid pathology in histopathological examination served as controls. In patients with PHPT there were 43 cases (84.3%) of coexistent thyroid pathology. Nine patients (17.6 %) had coexistent papillary thyroid cancer. Nine patients (17.6 %) had lymphocytic thyroiditis, two (3.9%) had benign thyroid adenoma and 24 (47%) had nodular hyperplasia. In one patient (2%), there was intrathyroidal metastasis from a parathyroid cancer. One patient had coexistent lymphocytic thyroiditis and multifocal papillary cancer. One of the two cases with thyroid adenomas was Hürthle cell type. In the control group only 28 patients (5.5%) had thyroid malignancy (27 papillary cancer and one follicular cancer). In conclusion, the coexistent thyroid pathologies are highly prevalent in patients with PHPT and pre- and intra-operative thyroid examination should be performed to avoid overlooking important thyroid pathologies.
- Subjects :
- Adolescent
Adult
Aged
Carcinoma, Papillary pathology
Carcinoma, Papillary prevention & control
Case-Control Studies
Comorbidity
Diagnostic Errors prevention & control
Female
Humans
Male
Middle Aged
Minimally Invasive Surgical Procedures
Thyroid Diseases pathology
Thyroid Diseases prevention & control
Thyroid Neoplasms pathology
Thyroid Neoplasms prevention & control
Turkey epidemiology
Carcinoma, Papillary epidemiology
Hyperparathyroidism epidemiology
Hyperparathyroidism surgery
Parathyroidectomy methods
Thyroid Diseases epidemiology
Thyroid Neoplasms epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 0001-5458
- Volume :
- 104
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- Acta chirurgica Belgica
- Publication Type :
- Academic Journal
- Accession number :
- 15571025
- Full Text :
- https://doi.org/10.1080/00015458.2004.11679616