VanE-type vancomycin-resistant Enterococcus faecalis clinical isolates from Australia.

Authors :: Abadía-Patiño L
Christiansen K
Bell J
Courvalin P
Périchon B
Source :: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2004 Dec; Vol. 48 (12), pp. 4882-5.
Publication Year :: 2004
Abstract: Three distinct Enterococcus faecalis VanE-type isolates-BM4574, BM4575, and BM4576-obtained in Australia were studied. Expression of the resistance genes was constitutive in BM4575, probably due to a 2-bp deletion into the vanSE gene, and inducible in BM4574 and BM4576. Transcription analysis of the vanE operons suggested that the five genes were cotranscribed from an initiation site located 25 bp upstream from the ATG start codon of vanE.

Subjects :: Australia
Chromosome Mapping
Codon genetics
DNA Primers
Electrophoresis, Gel, Pulsed-Field
Enterococcus faecalis enzymology
Operon genetics
Peptidoglycan metabolism
Reverse Transcriptase Polymerase Chain Reaction
Transcription, Genetic
Bacterial Proteins genetics
Enterococcus faecalis drug effects
Gram-Positive Bacterial Infections microbiology
Ligases genetics
Vancomycin Resistance genetics

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