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[Consensus-recommendations for sirolimus in liver transplantation].
- Source :
-
Zeitschrift fur Gastroenterologie [Z Gastroenterol] 2004 Nov; Vol. 42 (11), pp. 1333-40. - Publication Year :
- 2004
-
Abstract
- Sirolimus is an m-TOR inhibitor without renal side effects and potentially protects against the development of malignancy. Due to a higher incidence of complications in two trials and an official warning in the drug information, the use of Sirolimus in liver transplantation is limited. The participants of this consensus meeting had to analyse and evaluate the literature with respect to the potential role of Sirolimus in liver transplantation. This consensus statement follows the scheme normally employed for the presentation of guidelines including the grading of evidence (1a-5) and the extent of recommendation (A-C). Moreover, the consensus included the experience of the authors with respect to the handling of Sirolimus after liver transplantation.
- Subjects :
- Drug Therapy, Combination
Evidence-Based Medicine
Humans
Immunosuppressive Agents adverse effects
Practice Guidelines as Topic
Sirolimus adverse effects
Treatment Outcome
Graft Rejection drug therapy
Immunosuppressive Agents therapeutic use
Liver Transplantation immunology
Sirolimus therapeutic use
Subjects
Details
- Language :
- German
- ISSN :
- 0044-2771
- Volume :
- 42
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Zeitschrift fur Gastroenterologie
- Publication Type :
- Academic Journal
- Accession number :
- 15558447
- Full Text :
- https://doi.org/10.1055/s-2004-813703