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Forebrain sites of estradiol-17 beta action on sexual behavior and aggression in female Syrian hamsters.

Authors :
Sterner MR
Meisel RL
Diekman MA
Source :
Behavioral neuroscience [Behav Neurosci] 1992 Feb; Vol. 106 (1), pp. 162-71.
Publication Year :
1992

Abstract

The effects of intracranial implants of estradiol in the ventromedial hypothalamus (VMH), the anterior hypothalamus (AH), or the medial amygdala (AMG) on aggression, sexual behavior, and serum estradiol were examined in female Syrian hamsters. Estradiol implants in the VMH, followed by systemic progesterone, stimulated sexual behavior and inhibited aggression. Estradiol implants in other intracranial sites activated sexual behavior but did not reliably inhibit aggression. Intracranially implanted and systemically treated animals had equivalent peripheral estradiol concentrations at sacrifice. These results suggest that: (a) the VMH is an important neural site for estradiol actions on sexual and aggressive behavior, (b) the caudal AH and AMG also may be sites of estradiol action on sexual behavior, and (c) these intracranial implants may only be effective given systemic estradiol exposure or the concurrent stimulation of multiple brain areas.

Details

Language :
English
ISSN :
0735-7044
Volume :
106
Issue :
1
Database :
MEDLINE
Journal :
Behavioral neuroscience
Publication Type :
Academic Journal
Accession number :
1554429
Full Text :
https://doi.org/10.1037//0735-7044.106.1.162