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Forebrain sites of estradiol-17 beta action on sexual behavior and aggression in female Syrian hamsters.
- Source :
-
Behavioral neuroscience [Behav Neurosci] 1992 Feb; Vol. 106 (1), pp. 162-71. - Publication Year :
- 1992
-
Abstract
- The effects of intracranial implants of estradiol in the ventromedial hypothalamus (VMH), the anterior hypothalamus (AH), or the medial amygdala (AMG) on aggression, sexual behavior, and serum estradiol were examined in female Syrian hamsters. Estradiol implants in the VMH, followed by systemic progesterone, stimulated sexual behavior and inhibited aggression. Estradiol implants in other intracranial sites activated sexual behavior but did not reliably inhibit aggression. Intracranially implanted and systemically treated animals had equivalent peripheral estradiol concentrations at sacrifice. These results suggest that: (a) the VMH is an important neural site for estradiol actions on sexual and aggressive behavior, (b) the caudal AH and AMG also may be sites of estradiol action on sexual behavior, and (c) these intracranial implants may only be effective given systemic estradiol exposure or the concurrent stimulation of multiple brain areas.
- Subjects :
- Agonistic Behavior physiology
Animals
Brain Mapping
Cricetinae
Female
Progesterone physiology
Social Environment
Aggression physiology
Amygdala physiology
Estradiol physiology
Hypothalamus, Anterior physiology
Receptors, Estradiol physiology
Sexual Behavior, Animal physiology
Ventromedial Hypothalamic Nucleus physiology
Subjects
Details
- Language :
- English
- ISSN :
- 0735-7044
- Volume :
- 106
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Behavioral neuroscience
- Publication Type :
- Academic Journal
- Accession number :
- 1554429
- Full Text :
- https://doi.org/10.1037//0735-7044.106.1.162