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[A case of multiple pulmonary metastases from rectal cancer effectively treated by TS-1 and low-dose CDDP therapy].
- Source :
-
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 2004 Oct; Vol. 31 (10), pp. 1587-9. - Publication Year :
- 2004
-
Abstract
- We report a patient with multiple pulmonary metastases from rectal cancer effectively treated with TS-1 and low-dose CDDP combination chemotherapy. The patient was a 61-year-old man with rectal cancer and multiple pulmonary metastases. He had undergone abdominoperineal excision of the rectum at another hospital before this hospitalization. After the operation, we treated the patient by the combination chemotherapy of TS-1 and low-dose CDDP during his hospital stay and in the outpatient clinic after hospital discharge. After the chemotherapy was started, tumor markers decreased, and finally were in the normal range. The pulmonary metastatic lesions were remarkably reduced on CT, and the effect of this therapy was PR. No severe side effect was observed throughout the treatment. This combination chemotherapy is considered to be an effective therapy for colorectal cancer with good QOL.
- Subjects :
- Adenocarcinoma secondary
Adenocarcinoma surgery
Biomarkers, Tumor blood
Cisplatin administration & dosage
Combined Modality Therapy
Dose-Response Relationship, Drug
Drug Administration Schedule
Drug Combinations
Humans
Male
Middle Aged
Oxonic Acid administration & dosage
Pyridines administration & dosage
Rectal Neoplasms pathology
Rectal Neoplasms surgery
Remission Induction
Tegafur administration & dosage
Adenocarcinoma drug therapy
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Lung Neoplasms secondary
Rectal Neoplasms drug therapy
Subjects
Details
- Language :
- Japanese
- ISSN :
- 0385-0684
- Volume :
- 31
- Issue :
- 10
- Database :
- MEDLINE
- Journal :
- Gan to kagaku ryoho. Cancer & chemotherapy
- Publication Type :
- Academic Journal
- Accession number :
- 15508456