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The first regioselective palladium-catalyzed indolization of 2-bromo- or 2-chloroanilines with internal alkynes: a new approach to 2,3-disubstituted indoles.
- Source :
-
Organic letters [Org Lett] 2004 Oct 28; Vol. 6 (22), pp. 4129-32. - Publication Year :
- 2004
-
Abstract
- [reaction: see text] The first practical and economical process for synthesis of 2,3-disubstituted indole compounds has been developed with high regioselectivity by palladium-catalyzed indolization of 2-bromo- or chloroanilines and their derivatives with internal alkynes.
Details
- Language :
- English
- ISSN :
- 1523-7060
- Volume :
- 6
- Issue :
- 22
- Database :
- MEDLINE
- Journal :
- Organic letters
- Publication Type :
- Academic Journal
- Accession number :
- 15496116
- Full Text :
- https://doi.org/10.1021/ol048114t