Back to Search
Start Over
Dexamethasone and hypertension in preterm infants.
- Source :
-
European journal of pediatrics [Eur J Pediatr] 1992 Feb; Vol. 151 (2), pp. 134-5. - Publication Year :
- 1992
-
Abstract
- The magnitude and duration of the effect of dexamethasone on systolic blood pressure has been examined in 13 very preterm infants (median gestational age 25 weeks). All had chronic lung disease (CLD). To exclude any effect of CLD on blood pressure each infant acted as his or her own control. Systolic blood pressure increased in all infants (P less than 0.01) and remained elevated for at least 48h following cessation of therapy. The median maximum increase in blood pressure was 24 mmHg (range 13-49 mmHg) and occurred on day 4 (median, range 2-10) of treatment. One infant developed hypertensive encephalopathy. These results demonstrate the need to monitor infants with CLD throughout steroid therapy and preferably for some days after it has ceased.
- Subjects :
- Chronic Disease
Dexamethasone administration & dosage
Female
Gestational Age
Humans
Infant, Newborn
Infant, Premature, Diseases therapy
Lung Diseases therapy
Male
Time Factors
Ventilators, Mechanical
Dexamethasone adverse effects
Hypertension chemically induced
Infant, Premature, Diseases drug therapy
Lung Diseases drug therapy
Subjects
Details
- Language :
- English
- ISSN :
- 0340-6199
- Volume :
- 151
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- European journal of pediatrics
- Publication Type :
- Academic Journal
- Accession number :
- 1537356
- Full Text :
- https://doi.org/10.1007/BF01958959