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Synthesis of DNA mimics representing HypNA-pPNA hetero-oligomers.
- Source :
-
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2005; Vol. 288, pp. 147-64. - Publication Year :
- 2005
-
Abstract
- The methods for the synthesis and purification of negatively charged peptide nucleic acid (PNA)-relative deoxyribonucleic acid (DNA) mimics containing alternating residues of phosphono peptide nucleic acid (pPNA) monomers and PNA-like monomers on the base of trans-4-hydroxy-L-proline are described. Examples of the chimeric oligomers hybridization with complementary DNA and ribonucleic acid fragments are demonstrated.
Details
- Language :
- English
- ISSN :
- 1064-3745
- Volume :
- 288
- Database :
- MEDLINE
- Journal :
- Methods in molecular biology (Clifton, N.J.)
- Publication Type :
- Academic Journal
- Accession number :
- 15333902
- Full Text :
- https://doi.org/10.1385/1-59259-823-4:147