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[Effective treatment of liver metastasis and peritoneal dissemination of gastric cancer using intra-arterial therapy--a case report].
- Source :
-
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 1992 Aug; Vol. 19 (10 Suppl), pp. 1749-52. - Publication Year :
- 1992
-
Abstract
- A 56-year-old man who had undergone curative gastrectomy for Borrmann 2 type gastric cancer 43 months before, had a cancer recurrence (liver metastasis and peritoneal dissemination). Intra-arterial hypertensive chemotherapy with MMC for liver metastasis and intra-arterial sequential MTX/5-FU chemotherapy for peritoneal dissemination were given. He died of lung cancer with brain metastasis 27 months after this therapy. But in autopsy the remarkable effects of chemotherapy were recognized in intra-abdominal recurrent sites, and in fact, microscopically no cancer cells were found in metastatic lesions. We thus concluded that intra-arterial noradrenaline-induced hypertensive MMC therapy for liver metastasis and intra-arterial sequential MTX/5-FU therapy for peritoneal dissemination were useful treatment.
- Subjects :
- Blood Pressure
Drug Administration Schedule
Fluorouracil administration & dosage
Humans
Infusions, Intra-Arterial
Liver Neoplasms drug therapy
Liver Neoplasms physiopathology
Male
Methotrexate administration & dosage
Middle Aged
Mitomycin administration & dosage
Norepinephrine therapeutic use
Peritoneal Neoplasms drug therapy
Peritoneal Neoplasms physiopathology
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Liver Neoplasms secondary
Peritoneal Neoplasms secondary
Stomach Neoplasms pathology
Subjects
Details
- Language :
- Japanese
- ISSN :
- 0385-0684
- Volume :
- 19
- Issue :
- 10 Suppl
- Database :
- MEDLINE
- Journal :
- Gan to kagaku ryoho. Cancer & chemotherapy
- Publication Type :
- Academic Journal
- Accession number :
- 1530348