Back to Search
Start Over
Clinical symptoms in lumbar disc herniations and their correlation to the histological composition of the extruded disc material.
- Source :
-
Spine [Spine (Phila Pa 1976)] 2004 Aug 01; Vol. 29 (15), pp. 1655-61. - Publication Year :
- 2004
-
Abstract
- Study Design: Fifty-five consecutive patients undergoing microdiskectomy due to lumbar disc herniation were included in this clinical study over 12 months.<br />Objectives: To investigate possible correlations between the histologic composition of the herniated disc fragments and pain, disability, clinical signs, and operative findings.<br />Summary of Background Data: Previous studies have investigated the histologic composition of herniated lumbar disc fragments. Few publications, however, examined correlations with clinical data.<br />Methods: Before treatment, patients were examined using a standardized clinical protocol; subjective disability and pain were assessed by the Oswestry Disability Questionnaire and the McGill Pain Questionnaire. The herniated disc fragments were examined semiquantitatively for the relative percentages of nucleus pulposus, anulus fibrosus, and cartilaginous endplate.<br />Results: In patients less than 30 years of age, significantly higher percentages of nucleus pulposus were found than in the older group, whereas anulus fibrosus was found in significantly higher percentages in patients > or =30 years. Both higher percentages of cartilage and nucleus pulposus correlated with increased pain intensity values from the McGill Pain Questionnaire. Impaired reflexes before treatment occurred significantly more often in patients with > or =20% of cartilage in the herniated fragments. If nucleus pulposus was <30%, sensory impairment tended to be more severe before treatment.<br />Conclusion: The histologic composition of the herniated disc fragments seems to affect pain and clinical symptoms.
- Subjects :
- Adolescent
Adult
Aged
Disability Evaluation
Diskectomy
Female
Humans
Intervertebral Disc Displacement pathology
Intervertebral Disc Displacement surgery
Male
Middle Aged
Pain Measurement
Surveys and Questionnaires
Intervertebral Disc pathology
Intervertebral Disc Displacement diagnosis
Lumbar Vertebrae pathology
Subjects
Details
- Language :
- English
- ISSN :
- 1528-1159
- Volume :
- 29
- Issue :
- 15
- Database :
- MEDLINE
- Journal :
- Spine
- Publication Type :
- Academic Journal
- Accession number :
- 15284512
- Full Text :
- https://doi.org/10.1097/01.brs.0000133645.94159.64