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Male pseudohermaphroditism: long-term quality of life outcome in five 46,XY individuals reared female.
- Source :
-
Journal of pediatric endocrinology & metabolism : JPEM [J Pediatr Endocrinol Metab] 2004 Jun; Vol. 17 (6), pp. 809-23. - Publication Year :
- 2004
-
Abstract
- We assessed the adult quality of life of five medical chart-selected genetic males (ages 29-34 years) assigned and reared as females due to ambiguity of the external genitalia. All five were treated following the traditional method proposed by John Money and colleagues in 1955, commonly referred to as the "optimal gender policy". The adult follow-up assessment included physical and endocrinological evaluation, completion of self-report questionnaires, and a semi-structured interview assessing gender identity, sexual experience and orientation. Quality of life domains assessed by questionnaire included health-related issues, satisfaction with health-care management, emotional distress, and relationship satisfaction. Vaginoplasty in four out of five patients was initially unsuccessful. Four patients had periodic lapses in adherence to hormone replacement therapy. Gender role behavior across development was masculine relative to norms for women. All participants reported a female gender identity without a history of gender dysphoria. The majority of participants (four of five) reported being sexually active and in long-term relationships (three heterosexual, one homosexual). Current emotional adaptation and health-related quality of life are within the normal range for four participants. Sex assignment of 46,XY individuals with ambiguous genitalia as females is compatible with a positive quality of life.
- Subjects :
- Adult
Affective Symptoms etiology
Body Image
Child, Preschool
Disclosure
Estrogen Replacement Therapy
Female
Follow-Up Studies
Gonadal Dysgenesis, 46,XY complications
Gonadal Dysgenesis, 46,XY diagnosis
Gonadal Dysgenesis, 46,XY therapy
Health Status
Humans
Male
Marriage
Medical Records
Patient Satisfaction
Physical Examination
Sexual Behavior
Sexual Partners
Child Rearing
Disorders of Sex Development etiology
Gender Identity
Gonadal Dysgenesis, 46,XY physiopathology
Gonadal Dysgenesis, 46,XY psychology
Quality of Life
Subjects
Details
- Language :
- English
- ISSN :
- 0334-018X
- Volume :
- 17
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Journal of pediatric endocrinology & metabolism : JPEM
- Publication Type :
- Academic Journal
- Accession number :
- 15270399
- Full Text :
- https://doi.org/10.1515/jpem.2004.17.6.809