Xanthone isolated from Securidaca longependunculata with activity against erectile dysfunction.

Authors :: Rakuambo NC
Meyer JJ
Hussein A
Source :: Fitoterapia [Fitoterapia] 2004 Jul; Vol. 75 (5), pp. 497-9.
Publication Year :: 2004
Abstract: 1,7-Dimethoxy-2-hydroxy-xanthone and 1,4-dihydroxy-7-methoxy-xanthone isolated from Securidaca longependunculata were tested for their activity on rabbit corpus cavernosum in vitro. Only the former relaxed the corpus cavernosum by 63% at 1.8 x 10(-5) mg/ml.

Subjects :: Animals
Male
Muscle, Smooth drug effects
Plant Extracts administration & dosage
Plant Extracts therapeutic use
Plant Roots
Rabbits
Xanthones administration & dosage
Xanthones therapeutic use
Erectile Dysfunction drug therapy
Phytotherapy
Plant Extracts pharmacology
Securidaca
Xanthones pharmacology

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