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Cerebral ultrasound findings in neonatal lupus syndrome.
- Source :
-
Biology of the neonate [Biol Neonate] 2004; Vol. 86 (4), pp. 230-4. Date of Electronic Publication: 2004 Jul 14. - Publication Year :
- 2004
-
Abstract
- A prospective study was performed enrolling 11 newborns with neonatal lupus syndrome (NLS) and 22 control newborns to investigate cerebral ultrasound (US) anomalies and their relationship with clinical neurological signs and laboratory findings. Cerebral US detected a significantly higher incidence in the study group of both subependymal pseudocysts (SEPC) and subependymal hemorrhage (SEH), neither of which correlated to autoantibody levels. All infants had completely normal neurological examinations both at birth and follow-up. The etiopathogenesis of central nervous system findings in NLS is discussed. US evaluation identified minimal anomalies compatible with favorable outcome: further studies are necessary to investigate the possible long-term sequelae, pathogenesis and spectrum of cerebral US findings.<br /> (2004 S. Karger AG, Basel.)
- Subjects :
- Autoantibodies immunology
Autoantigens
Brain Diseases diagnostic imaging
Cerebral Hemorrhage diagnostic imaging
Cysts diagnostic imaging
Female
Follow-Up Studies
Humans
Infant, Newborn
Lupus Vulgaris immunology
Male
Prospective Studies
Ribonucleoproteins immunology
Syndrome
SS-B Antigen
Echoencephalography
Lupus Vulgaris diagnostic imaging
Subjects
Details
- Language :
- English
- ISSN :
- 0006-3126
- Volume :
- 86
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Biology of the neonate
- Publication Type :
- Academic Journal
- Accession number :
- 15256800
- Full Text :
- https://doi.org/10.1159/000079820