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Cerebral ultrasound findings in neonatal lupus syndrome.

Authors :
Zuppa AA
Gallini F
De Luca D
Luciano R
Frezza S
de Turris PL
Tortorolo G
Source :
Biology of the neonate [Biol Neonate] 2004; Vol. 86 (4), pp. 230-4. Date of Electronic Publication: 2004 Jul 14.
Publication Year :
2004

Abstract

A prospective study was performed enrolling 11 newborns with neonatal lupus syndrome (NLS) and 22 control newborns to investigate cerebral ultrasound (US) anomalies and their relationship with clinical neurological signs and laboratory findings. Cerebral US detected a significantly higher incidence in the study group of both subependymal pseudocysts (SEPC) and subependymal hemorrhage (SEH), neither of which correlated to autoantibody levels. All infants had completely normal neurological examinations both at birth and follow-up. The etiopathogenesis of central nervous system findings in NLS is discussed. US evaluation identified minimal anomalies compatible with favorable outcome: further studies are necessary to investigate the possible long-term sequelae, pathogenesis and spectrum of cerebral US findings.<br /> (2004 S. Karger AG, Basel.)

Details

Language :
English
ISSN :
0006-3126
Volume :
86
Issue :
4
Database :
MEDLINE
Journal :
Biology of the neonate
Publication Type :
Academic Journal
Accession number :
15256800
Full Text :
https://doi.org/10.1159/000079820