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Human anaplasmosis in north-eastern Poland: seroprevalence in humans and prevalence in Ixodes ricinus ticks.
- Source :
-
Annals of agricultural and environmental medicine : AAEM [Ann Agric Environ Med] 2004; Vol. 11 (1), pp. 99-103. - Publication Year :
- 2004
-
Abstract
- Sera of 500 inhabitants of north-eastern Poland, 450 suspected for Lyme borreliosis and 50 blood donors (control group), were analysed for the presence of IgG antibodies against Anaplasma phagocytophilum, the causative agent of human anaplasmosis (HA), known so far as human granulocytic ehrlichiosis (HGE). Forty one (9.1 %) sera of the study group and one serum (2 %) of the control group were positive using indirect fluorescence assay (IFA). The seropositivity tended to be more frequent among males (10.3 %) than females (7.6 %) and among the rural (10.3 %) than urban population (7.5 %); however, differences were of no statistical significance (p = 0.4). No age difference was found between the seropositive and the seronegative individuals (p = 0.77). The only factor increasing the risk of HA seropositivity found was forestry employment (p < 0.05). Additionally, a total of 559 Ixodes ricinus ticks, collected in the same area as sera, were investigated for the presence of A. phagocytophilum by the polymerase chain reaction (PCR) and 41 (8.7 %) of them were found to be positive. The infection level ranged from 2.3-13.7 %, depending on the area studied. Bacteria were significantly less frequently detected in nymphs - 2.1 % (5/235) than in adult ticks - 13.6 % (44/324) and in males--4.2 % (74/165) than in females--23.3 % (37/159) (p < or = 0.05). The obtained results confirm both the occurrence of HA foci in north-eastern Poland with I. ricinus as the principal vector of the A. phagocytophilum infection, and forestry workers as the main group at risk.
- Subjects :
- Adult
Anaplasma phagocytophilum immunology
Animals
Case-Control Studies
DNA, Bacterial analysis
Ehrlichiosis epidemiology
Female
Fluorescent Antibody Technique, Indirect
Forestry
Humans
Immunoglobulin G blood
Lyme Disease epidemiology
Male
Odds Ratio
Poland epidemiology
Polymerase Chain Reaction
Risk Assessment
Rural Population statistics & numerical data
Seroepidemiologic Studies
Statistics, Nonparametric
Urban Population statistics & numerical data
Anaplasma phagocytophilum isolation & purification
Antibodies, Bacterial blood
Borrelia burgdorferi Group isolation & purification
Ehrlichiosis transmission
Ixodes microbiology
Lyme Disease transmission
Subjects
Details
- Language :
- English
- ISSN :
- 1232-1966
- Volume :
- 11
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Annals of agricultural and environmental medicine : AAEM
- Publication Type :
- Academic Journal
- Accession number :
- 15236505