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[Cellular immunity in patients with urogenital chlamydiosis].

Authors :
Mikolauskas VP
Source :
Klinicheskaia laboratornaia diagnostika [Klin Lab Diagn] 2004 Apr (4), pp. 36-8.
Publication Year :
2004

Abstract

Abnormalities in the cellular immunity chain (CIC) were found in 63.04% of patients with urogenital chlamydiosis (UGC) within a study of cellular immunity in patients with the above pathology. According to the study results, the below listed were the main CIC impairments: a lack or reaction to the inducer of T-helpers (CD3+ and CD4+), and to activated T-lymphocytes (CD3+ and CD25+); higher counts of cytotoxic T-lymphocytes (CD3+ and CD8+), a higher content of B-lymphocytes (CD3+ and CD19+, and lower counts of NK-cells (CD3- and CD56+). However, research of the lymphocyte subpopulation alone is not enough to evaluate adequately the immune system of a patient. In order to choose an adequate scheme for the treatment of UGH patients it is necessary to undertake a study of the immune status that should comprise, apart CIC investigations, the following: humoral immunity, phagocyte function, factors of non-specific body resistance and cytokine status.

Details

Language :
Russian
ISSN :
0869-2084
Issue :
4
Database :
MEDLINE
Journal :
Klinicheskaia laboratornaia diagnostika
Publication Type :
Academic Journal
Accession number :
15188743