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[Relationship between the obstructive sleep apnea syndrome and internal medicine].
- Source :
-
Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna [Ann Ital Med Int] 2004 Jan-Mar; Vol. 19 (1), pp. 43-9. - Publication Year :
- 2004
-
Abstract
- Twelve to twenty-five percent of human population suffer from sleep disorders and sleep-related breathing disorders have a frequency of 5-10%. The association between sleep-related breathing disorders and several diseases, mainly cardiovascular and dysmetabolic, is well known. The aim of this study was to assess the prevalence of this association in a group of 620 patients, aged between 18 and 78 years and referred to the Laboratory of Respiratory Pathophysiology of the Umberto I Hospital of Rome. All patients had a clinical history of a sleep-related breathing disorder and answered a specific questionnaire. One-hundred-and-thirty-seven patients (120 males and 17 females, mean age 64 years), whose questionnaire was suggestive of a sleep-related breathing disorder, underwent clinical assessment including blood tests, lung function tests, blood-gas analysis, ECG and nocturnal polysomnography, either as in- or as out-patients. The main associated pathologies were: arterial hypertension (54.7%), chronic obstructive pulmonary disease (17.9%), obesity (63.1%), dyslipidemia (41%), type 2 diabetes mellitus (6.3%), gastroesophageal reflux (27.3%) and cardiac arrhythmias (4.2%); 95 patients with obstructive sleep apnea syndrome were treated, on the basis of the polysomnography outcomes and according to the Italian Association of Sleep Medicine Guidelines, either with preventive strategies for risk factor reduction, or with medical (positive pressure ventilation, oxygen, assessment of the best drug medication) and/or ear, nose end throat surgical therapies. In most patients, the improvement in the sleep-related breathing disorder was associated with an improvement in their systemic pathology, in particular cardiovascular disease, suggesting the need of a deeper consideration and comprehension of nocturnal apneas.
- Subjects :
- Adolescent
Adult
Aged
Cardiovascular Diseases epidemiology
Cardiovascular Diseases etiology
Comorbidity
Female
Gastroesophageal Reflux epidemiology
Gastroesophageal Reflux etiology
Humans
Male
Middle Aged
Obesity epidemiology
Polysomnography
Positive-Pressure Respiration
Pulmonary Disease, Chronic Obstructive epidemiology
Risk Factors
Rome epidemiology
Sleep Wake Disorders epidemiology
Surveys and Questionnaires
Internal Medicine
Sleep Apnea, Obstructive complications
Sleep Apnea, Obstructive epidemiology
Sleep Apnea, Obstructive metabolism
Sleep Apnea, Obstructive physiopathology
Sleep Apnea, Obstructive therapy
Subjects
Details
- Language :
- Italian
- ISSN :
- 0393-9340
- Volume :
- 19
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna
- Publication Type :
- Academic Journal
- Accession number :
- 15176707