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Detection of EHV-1 and EHV-4 DNA in unweaned Thoroughbred foals from vaccinated mares on a large stud farm.
- Source :
-
Equine veterinary journal [Equine Vet J] 2004 May; Vol. 36 (4), pp. 341-5. - Publication Year :
- 2004
-
Abstract
- Reasons for Performing Study: A silent cycle of equine herpesvirus 1 infection has been described following epidemiological studies in unvaccinated mares and foals. In 1997, an inactivated whole virus EHV-1 and EHV-4 vaccine was released commercially in Australia and used on many stud farms. However, it was not known what effect vaccination might have on the cycle of infection of EHV-1.<br />Objective: To investigate whether EHV-1 and EHV-4 could be detected in young foals from vaccinated mares.<br />Methods: Nasal and blood samples were tested by PCR and ELISA after collection from 237 unvaccinated, unweaned foals and vaccinated and nonvaccinated mares during the breeding season of 2000.<br />Results: EHV-1 and EHV-4 DNA was detected in nasal swab samples from foals as young as age 11 days.<br />Conclusions: These results confirm that EHV-1 and EHV-4 circulate in vaccinated populations of mares and their unweaned, unvaccinated foals.<br />Potential Relevance: The evidence that the cycle of EHV-1 and EHV-4 infection is continuing and that very young foals are becoming infected should assist stud farms in their management of the threat posed by these viruses.
- Subjects :
- Animals
Animals, Suckling
Antibodies, Viral blood
Australia epidemiology
DNA, Viral isolation & purification
Disease Reservoirs veterinary
Enzyme-Linked Immunosorbent Assay veterinary
Female
Herpesviridae Infections immunology
Herpesviridae Infections transmission
Herpesvirus 1, Equid genetics
Herpesvirus 1, Equid immunology
Herpesvirus 4, Equid genetics
Herpesvirus 4, Equid immunology
Herpesvirus Vaccines administration & dosage
Horse Diseases blood
Horse Diseases immunology
Horses
Male
Nasal Mucosa virology
Polymerase Chain Reaction veterinary
Seroepidemiologic Studies
Vaccines, Inactivated administration & dosage
Vaccines, Inactivated immunology
Herpesviridae Infections veterinary
Herpesvirus 1, Equid isolation & purification
Herpesvirus 4, Equid isolation & purification
Herpesvirus Vaccines immunology
Horse Diseases transmission
Infectious Disease Transmission, Vertical veterinary
Subjects
Details
- Language :
- English
- ISSN :
- 0425-1644
- Volume :
- 36
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Equine veterinary journal
- Publication Type :
- Academic Journal
- Accession number :
- 15163042
- Full Text :
- https://doi.org/10.2746/0425164044890634