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CuI/N,N-dimethylglycine-catalyzed coupling of vinyl halides with amides or carbamates.

Authors :
Pan X
Cai Q
Ma D
Source :
Organic letters [Org Lett] 2004 May 27; Vol. 6 (11), pp. 1809-12.
Publication Year :
2004

Abstract

The CuI-catalyzed coupling reaction of vinyl halides with amides or carbamates proceeds well at room temperature to 80 degrees C in dioxane to give enamides using N,N-dimethylglycine as the promoter and Cs(2)CO(3) as the base. The geometry of the C-C double bond is retained during the reaction course. [reaction: see text]

Details

Language :
English
ISSN :
1523-7060
Volume :
6
Issue :
11
Database :
MEDLINE
Journal :
Organic letters
Publication Type :
Academic Journal
Accession number :
15151420
Full Text :
https://doi.org/10.1021/ol049464i