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Prevalence of beta2-glycoprotein I antibody in patients with liver cirrhosis: relationship with beta2-glycoprotein I plasma levels and thrombosis.
- Source :
-
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis [Clin Appl Thromb Hemost] 2004 Apr; Vol. 10 (2), pp. 183-6. - Publication Year :
- 2004
-
Abstract
- Recently, a semiquantitative enzyme-linked immunoassay for detecting IgG or IgM class autoantibody to beta2-GPI for use as an aid in the diagnosis of certain autoimmune or thrombotic disorders. We evaluated the prevalence of anti-beta2-GPI antibody and its relation to plasma beta2-GPI levels and occurrence of thrombosis in 69 patients with liver cirrhosis. As expected, plasma beta2-GPI levels were lower in the patients with liver cirrhosis and correlated with Child classification. Anti-beta2-GPI antibodies were positive in 11 (15.9%) patients. However, there were no differences in beta2-GPI levels, platelet counts, and thrombosis between positive and negative groups for anti-beta2-GPI antibodies.
- Subjects :
- Female
Humans
Liver Cirrhosis diagnosis
Male
Middle Aged
Platelet Count
Prevalence
Thrombosis diagnosis
Thrombosis immunology
beta 2-Glycoprotein I
Autoantibodies analysis
Autoantibodies immunology
Glycoproteins blood
Glycoproteins immunology
Liver Cirrhosis blood
Liver Cirrhosis immunology
Thrombosis blood
Subjects
Details
- Language :
- English
- ISSN :
- 1076-0296
- Volume :
- 10
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
- Publication Type :
- Academic Journal
- Accession number :
- 15094940
- Full Text :
- https://doi.org/10.1177/107602960401000210