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The correlation between plasma homocysteine and malondialdehyde levels in preeclampsia.

Authors :
Tug N
Celik H
Cikim G
Ozcelik O
Ayar A
Source :
Neuro endocrinology letters [Neuro Endocrinol Lett] 2003 Dec; Vol. 24 (6), pp. 445-8.
Publication Year :
2003

Abstract

Objective: To investigate the possible correlation between plasma malondialdehyde and homocysteine levels of preeclamptic patients.<br />Design: Venous blood samples of 20 preeclamptics and 20 healthy pregnant controls were collected. Plasma malondialdehyde and homocysteine concentrations were measured and the correlation between them was investigated. Mann Whitney U test and Spearman correlation analysis were used for statistical analysis.<br />Setting: University of Firat, Medical School.<br />Results: Plasma malondialdehyde and homocysteine concentrations were higher in preeclamptic patients (p<0.05) and a positive correlation between these parameters was found (r: 0.77, p<0.01, n:20).<br />Conclusion: Our results may put forward some new strategies in the research of etiopathogenesis and treatment of preeclampsia.

Details

Language :
English
ISSN :
0172-780X
Volume :
24
Issue :
6
Database :
MEDLINE
Journal :
Neuro endocrinology letters
Publication Type :
Academic Journal
Accession number :
15073573