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[Effect of yirong oral liquid on the reperfusion injury in rats with cerebral infarction undergoing thrombolysis].
- Source :
-
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine [Zhongguo Zhong Xi Yi Jie He Za Zhi] 2004 Feb; Vol. 24 (2), pp. 143-6. - Publication Year :
- 2004
-
Abstract
- Objective: To observe the effect of Yirong Oral Liquid (YROL) on reperfusion injury in rats with cerebral infarction undergoing thrombolysis.<br />Methods: Clinical reperfusion under thrombolysis was simulated by applying thrombolysis on reversible local cerebral ischemic rat model. In the rat model, effect of YROL on parameters concerning anti-oxidation capability, cerebral edema and ultrastructure of brain were observed.<br />Results: YROL could alleviate the cerebral edema after reperfusion, markedly increase the activity of superoxide dismutase in blood plasma, decrease the content of malonyldialdehyde, inhibit the post-reperfusion lipid peroxidation, and significantly reduce the ischemia/reperfusion injury of nerve cells in brain of rat.<br />Conclusion: YROL has definite protecting effect on brain.
- Subjects :
- Animals
Cerebral Infarction pathology
Drug Therapy, Combination
Male
Malondialdehyde blood
Rats
Rats, Sprague-Dawley
Superoxide Dismutase blood
Urokinase-Type Plasminogen Activator therapeutic use
Cerebral Infarction drug therapy
Drugs, Chinese Herbal therapeutic use
Neuroprotective Agents therapeutic use
Phytotherapy
Reperfusion Injury prevention & control
Thrombolytic Therapy
Subjects
Details
- Language :
- Chinese
- ISSN :
- 1003-5370
- Volume :
- 24
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine
- Publication Type :
- Academic Journal
- Accession number :
- 15015450