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Oral antivirals for the acute treatment of recurrent herpes labialis.
- Source :
-
The Annals of pharmacotherapy [Ann Pharmacother] 2004 Apr; Vol. 38 (4), pp. 705-9. Date of Electronic Publication: 2004 Feb 13. - Publication Year :
- 2004
-
Abstract
- Objective: To evaluate the use and benefit of oral antivirals in the acute treatment of episodic, recurrent herpes labialis.<br />Data Sources: A literature search was performed in MEDLINE (1966-August 2003) using acyclovir, famciclovir, valacyclovir, cold sores, herpes labialis, and HSV-1 as search terms.<br />Data Synthesis: We reviewed 5 placebo-controlled and 2 comparative studies evaluating oral antivirals for acute treatment of recurrent herpes labialis. No studies directly compared different antivirals. Studies discussing the efficacy of antivirals for chronic suppression of herpes simplex virus-1 infection were not included.<br />Conclusions: Treatment with oral antivirals decreases the duration of lesion episodes and pain by approximately one day; however, the antivirals do not abort lesions from developing. Clinical implications of these results appear relatively modest.
- Subjects :
- 2-Aminopurine economics
2-Aminopurine therapeutic use
Acyclovir economics
Acyclovir therapeutic use
Administration, Oral
Antiviral Agents economics
Clinical Trials as Topic
Famciclovir
Humans
Recurrence
Valacyclovir
Valine economics
Valine therapeutic use
2-Aminopurine analogs & derivatives
Acyclovir analogs & derivatives
Antiviral Agents therapeutic use
Herpes Labialis drug therapy
Valine analogs & derivatives
Subjects
Details
- Language :
- English
- ISSN :
- 1060-0280
- Volume :
- 38
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- The Annals of pharmacotherapy
- Publication Type :
- Academic Journal
- Accession number :
- 14966254
- Full Text :
- https://doi.org/10.1345/aph.1D285