[Use of enalapril in the preparation of patients with arterial hypertension to the surgical procedures].

Aim: To study efficacy of enalapril, ACE inhibitor, in preparation to surgery of hypertensive patients with concomitant surgical diseases.
Material and Methods: An open controlled randomised study of the action of enalapril preoperative therapy on hemodynamics was made in 55 hypertensive patients aged 36-68 years with surgical abdominal diseases.
Results: Before surgery, the study group of 30 patients were given enalapril for a month. The control group of 24 patients received a month therapy with adelphan and papasol. The study group achieved a greater fall in the morning and evening systolic arterial pressure and morning diastolic pressure. These falls allowed elective operative interventions. Intraoperative hyperdynamic reactions, cardiac arrhythmia, intraoperative myocardial ischemia occurred less frequently in the study group. Enalapril provided better intraoperative peripheral blood saturation with oxygen.
Conclusion: Enalapril, an ACE inhibitor, can be used as a hypotensive drug for preparation of hypertensive patients for elective surgery because it regulates processes providing effective stabilization of arterial pressure, adequate supply of oxygen to peripheral blood.