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Significance of syncope in patients with Alzheimer's disease treated with cholinesterase inhibitors.
- Source :
-
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology [Europace] 2003 Oct; Vol. 5 (4), pp. 429-31. - Publication Year :
- 2003
-
Abstract
- We describe three cases of patients with Alzheimer's disease who presented with cardiac syncope soon after initiation of a cholinesterase inhibitor therapy (donepezil). Bradyarrhythmia was documented in two patients, considered probable in one, and was presumed related to the cholinergic therapy. Pacemaker implantation seemed justified rather than donepezil cessation. More over, it permitted an increase in donepezil dosage.
- Subjects :
- Aged
Aged, 80 and over
Alzheimer Disease complications
Bradycardia chemically induced
Bradycardia prevention & control
Cholinesterase Inhibitors therapeutic use
Donepezil
Female
Humans
Indans therapeutic use
Male
Pacemaker, Artificial
Piperidines therapeutic use
Alzheimer Disease drug therapy
Cholinesterase Inhibitors adverse effects
Indans adverse effects
Piperidines adverse effects
Syncope etiology
Subjects
Details
- Language :
- English
- ISSN :
- 1099-5129
- Volume :
- 5
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
- Publication Type :
- Academic Journal
- Accession number :
- 14753643
- Full Text :
- https://doi.org/10.1016/s1099-5129(03)00080-1