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[A case of rectal cancer with distant lymph node metastases completely responding to postoperative chemotherapy with levofolinate combined with 5-fluorouracil].
- Source :
-
Gan to kagaku ryoho. Cancer & chemotherapy [Gan To Kagaku Ryoho] 2004 Jan; Vol. 31 (1), pp. 117-9. - Publication Year :
- 2004
-
Abstract
- The patient was a 58-year-old female who had a cancer of the rectum with multiple lymph node metastases including paraaortic lymph nodes and Virchow lymph nodes. Abdominoperineal resection was performed palliatively. After the operation, weekly bolus of 5-fluorouracil combined with levofolinate was carried out. After 2 courses of chemotherapy, metastases of paraaortic lymph nodes and Virchow lymph nodes completely disappeared upon CT examination. Chemotherapy has continued for 14 months, and she is well and has maintained a complete response for more than 1 year. This case suggests that this combination chemotherapy of LV/5-FU, admitted in Japan, is effective against advanced colorectal cancer.
- Subjects :
- Drug Administration Schedule
Female
Fluorouracil administration & dosage
Humans
Leucovorin administration & dosage
Lymphatic Metastasis
Middle Aged
Remission Induction
Adenocarcinoma drug therapy
Adenocarcinoma secondary
Antineoplastic Combined Chemotherapy Protocols therapeutic use
Lymph Nodes pathology
Rectal Neoplasms drug therapy
Rectal Neoplasms pathology
Subjects
Details
- Language :
- Japanese
- ISSN :
- 0385-0684
- Volume :
- 31
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- Gan to kagaku ryoho. Cancer & chemotherapy
- Publication Type :
- Academic Journal
- Accession number :
- 14750335