Back to Search
Start Over
Amino acids as regulators of gene expression: molecular mechanisms.
- Source :
-
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2004 Jan 09; Vol. 313 (2), pp. 447-52. - Publication Year :
- 2004
-
Abstract
- Regulation of gene expression by nutrients in mammals is an important mechanism allowing them to adapt their physiological functions according to the supply of nutrient in the diet. It has been shown recently that amino acids are able to regulate by themselves the expression of numerous genes. CHOP, asparagine synthetase, and IGFBP-1 regulation following AA starvation will be described in this review with special interest in the molecular mechanisms involved.
- Subjects :
- Activating Transcription Factor 4
Animals
Aspartate-Ammonia Ligase metabolism
CCAAT-Enhancer-Binding Proteins genetics
CCAAT-Enhancer-Binding Proteins metabolism
Dietary Supplements
Gene Expression Regulation drug effects
Humans
Insulin-Like Growth Factor Binding Protein 1 metabolism
Starvation metabolism
Stress, Physiological metabolism
Transcription Factor CHOP
Transcription Factors genetics
Transcription Factors metabolism
Transcription, Genetic
Amino Acids pharmacology
Amino Acids physiology
Gene Expression Regulation physiology
Subjects
Details
- Language :
- English
- ISSN :
- 0006-291X
- Volume :
- 313
- Issue :
- 2
- Database :
- MEDLINE
- Journal :
- Biochemical and biophysical research communications
- Publication Type :
- Academic Journal
- Accession number :
- 14684183
- Full Text :
- https://doi.org/10.1016/j.bbrc.2003.07.020