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Synthesis of 2-(3'-azido- and 3'-amino-3'-deoxy-beta-D-ribofuranosyl)thiazole-4-carboxamide.
- Source :
-
Nucleosides, nucleotides & nucleic acids [Nucleosides Nucleotides Nucleic Acids] 2003 Nov; Vol. 22 (11), pp. 2039-48. - Publication Year :
- 2003
-
Abstract
- In view of biological activities of tiazofurin and azido or aminosugar nucleosides, novel azido- and amino-substituted tiazofurin derivatives (1 and 2) were efficiently synthesized starting from 1,2;5,6-di-O-isopropylidene-D-glucose.
- Subjects :
- Animals
Antineoplastic Agents chemical synthesis
Antineoplastic Agents pharmacology
Enzyme Inhibitors chemistry
Enzyme Inhibitors pharmacology
Nucleosides chemical synthesis
Nucleosides pharmacology
Ribavirin chemistry
Ribavirin pharmacology
Enzyme Inhibitors chemical synthesis
Ribavirin analogs & derivatives
Ribavirin chemical synthesis
Subjects
Details
- Language :
- English
- ISSN :
- 1525-7770
- Volume :
- 22
- Issue :
- 11
- Database :
- MEDLINE
- Journal :
- Nucleosides, nucleotides & nucleic acids
- Publication Type :
- Academic Journal
- Accession number :
- 14680026
- Full Text :
- https://doi.org/10.1081/NCN-120026405