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[Transfusion-associated graft-vs-host disease in a patient with Hodgkin's disease].
- Source :
-
Ugeskrift for laeger [Ugeskr Laeger] 1992 Oct 19; Vol. 154 (43), pp. 2979-80. - Publication Year :
- 1992
-
Abstract
- Transfusion-associated graft-versus-host disease (TA-GVHD) is a serious complication of blood transfusion which is caused by immunocompetent donor lymphocytes reacting against recipient antigens. We report a case of TA-GVHD in a male patient with Hodgkin's disease who had received several units of non-irradiated blood components. TA-GVHD was diagnosed by histological examination of affected skin and demonstration of engrafted lymphocytes of female phenotype by in situ hybridization using a Y-chromosome specific probe. The need to irradiate blood components given to patients in defined risk-groups is stressed.
Details
- Language :
- Danish
- ISSN :
- 0041-5782
- Volume :
- 154
- Issue :
- 43
- Database :
- MEDLINE
- Journal :
- Ugeskrift for laeger
- Publication Type :
- Academic Journal
- Accession number :
- 1462387