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[Polymerase chain reaction in the diagnosis of viral infections in the newborn].
- Source :
-
Vestnik Rossiiskoi akademii meditsinskikh nauk [Vestn Ross Akad Med Nauk] 2003 (9), pp. 37-9. - Publication Year :
- 2003
-
Abstract
- Two hundred and ten newborns from among a high risk group were examined for intrauterine infections by polymerase chain reaction (PCR) with the aim of assessing the clinical information density of the method in the diagnostic sphere. The patients were examined for the presence of DNA/RNA viruses and bacteria. Genetic samples of various causative agents were detected in 49% of the newborns. No correlation was established between the clinical pattern and the presence of DNA of certain microorganisms. The most severe condition of newborns was noted in cases when a DNA causative agent was found in several different biological samples. The highest mortality (in per cent) was registered in the group of newborns with detected DNA of Herpesviridae viruses. The PCR clinical value was affirmed for establishing a disease etiology in newborns.
- Subjects :
- Adolescent
Adult
Age Factors
Blood microbiology
Cerebrospinal Fluid microbiology
DNA, Viral analysis
Female
Herpesviridae Infections blood
Herpesviridae Infections cerebrospinal fluid
Herpesviridae Infections diagnosis
Herpesviridae Infections genetics
Herpesviridae Infections mortality
Humans
Infant, Newborn
Male
Maternal Age
RNA, Viral analysis
Risk Factors
Virus Diseases blood
Virus Diseases cerebrospinal fluid
Virus Diseases genetics
Virus Diseases mortality
Polymerase Chain Reaction
Virus Diseases diagnosis
Subjects
Details
- Language :
- Russian
- ISSN :
- 0869-6047
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Vestnik Rossiiskoi akademii meditsinskikh nauk
- Publication Type :
- Academic Journal
- Accession number :
- 14598735