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The chemokine receptor, CCR5.
- Source :
-
The international journal of biochemistry & cell biology [Int J Biochem Cell Biol] 2004 Jan; Vol. 36 (1), pp. 35-8. - Publication Year :
- 2004
-
Abstract
- The chemokine receptor, CCR5, is a G protein coupled receptor responsible for some of the effects of the chemokines CCL3, CCL4 and CCL5. It is also one of the co-receptors for the entry of human immunodeficiency virus-1 (HIV-1) into cells. Regulation of CCR5 number on cells is, therefore, important for determining the infection rate by HIV-1.
- Subjects :
- Amino Acid Sequence
Animals
Chromosomes, Human, Pair 3
Frameshift Mutation
Gene Frequency
HIV Infections immunology
HIV-1 immunology
Humans
Polymorphism, Genetic
Protein Structure, Secondary
Receptors, CCR5 genetics
Receptors, CCR5 immunology
Receptors, CCR5 chemistry
Receptors, CCR5 physiology
Subjects
Details
- Language :
- English
- ISSN :
- 1357-2725
- Volume :
- 36
- Issue :
- 1
- Database :
- MEDLINE
- Journal :
- The international journal of biochemistry & cell biology
- Publication Type :
- Academic Journal
- Accession number :
- 14592532
- Full Text :
- https://doi.org/10.1016/s1357-2725(03)00172-9