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Pattern of contact sensitivity in Indian patients with hand eczema.
- Source :
-
The Journal of dermatology [J Dermatol] 2003 Sep; Vol. 30 (9), pp. 649-54. - Publication Year :
- 2003
-
Abstract
- One hundred consecutive patients with hand eczema were patch tested with the Indian Standard Series and indigenous antigens after a detailed history and clinical examination. Both sexes were involved and the majority of them were in the age group between 20-39 years (56%). Their occupational profile varied in order of frequency from household work (37%), to masons (14%), students (11%), factory workers (7%), and others (31%). Itching was the most common presenting complaint (93%). A history of atopy was found in 36% of the patients. The predominant sites involved were the palms (43%), followed by fingers (32%), dorsum (17%), and the entire hand (8%). Dry, scaly skin was the most common morphological picture, followed by hyperpigmentation, fissuring, and lichenification. Based on history, clinical examination and patch test results, the diagnosis was made as allergic contact dermatitis in 67% of cases and irritant contact dermatitis in 15% of cases. Positive patch tests with one or more allergens were noted in 67% of the patients. Vegetables (21%) were found to be the most common sensitizers, followed by nickel sulphate (20%), potassium dichromate (18%), and others. Wet work, soaps, and detergents were found to be the most offending irritants. The present study confirmed the fact that hand eczema is a multifactorial disease caused by both irritants and allergens.
- Subjects :
- Adolescent
Adult
Allergens adverse effects
Child
Dermatitis, Allergic Contact etiology
Dermatitis, Allergic Contact genetics
Dermatitis, Allergic Contact pathology
Dermatitis, Occupational epidemiology
Dermatitis, Occupational etiology
Detergents adverse effects
Eczema etiology
Eczema genetics
Eczema pathology
Female
Hand Dermatoses etiology
Hand Dermatoses genetics
Hand Dermatoses pathology
Humans
India epidemiology
Male
Middle Aged
Patch Tests
Sex Distribution
White People genetics
Dermatitis, Allergic Contact epidemiology
Eczema epidemiology
Hand Dermatoses epidemiology
Subjects
Details
- Language :
- English
- ISSN :
- 0385-2407
- Volume :
- 30
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- The Journal of dermatology
- Publication Type :
- Academic Journal
- Accession number :
- 14578554
- Full Text :
- https://doi.org/10.1111/j.1346-8138.2003.tb00453.x