Back to Search
Start Over
[Tetracyclines, sulfonamides and metronidazole].
- Source :
-
Enfermedades infecciosas y microbiologia clinica [Enferm Infecc Microbiol Clin] 2003 Nov; Vol. 21 (9), pp. 520-8; quiz 529, 533. - Publication Year :
- 2003
-
Abstract
- Tetracyclines form a group of natural and semisynthetic products that acts inhibiting the bacterial protein synthesis. They are bacteriostatic agents, exhibiting activity against a wide range of organisms, but they are at the present of limited use because of their acquired resistance. Doxycycline is currently the most frequently used tetracycline in human medicine and it is included in the List of Essential Medicines of the World Health Organization. Sulfonamides are synthetic, broad-spectrum bacteriostatic antibiotics. They were the first effective systemic antimicrobial agents. Their mode of action is based on the inhibition of DNA synthesis. Due to their toxicity and high adquired resistance their use is currently very low. Metronidazole is the main compound of 5-nitroimidazole family. It is a very active bactericidal antibiotic against anaerobic and some microaerophilic bacteria and it is still very useful in the treatment of bacterian and parasitic infections.
- Subjects :
- Bacterial Infections drug therapy
Contraindications
DNA Replication drug effects
Humans
Molecular Structure
Parasitic Diseases drug therapy
Anti-Infective Agents adverse effects
Anti-Infective Agents chemistry
Anti-Infective Agents pharmacology
Anti-Infective Agents therapeutic use
Metronidazole adverse effects
Metronidazole chemistry
Metronidazole pharmacology
Metronidazole therapeutic use
Sulfanilamides adverse effects
Sulfanilamides chemistry
Sulfanilamides pharmacology
Sulfanilamides therapeutic use
Tetracyclines adverse effects
Tetracyclines chemistry
Tetracyclines pharmacology
Tetracyclines therapeutic use
Subjects
Details
- Language :
- Spanish; Castilian
- ISSN :
- 0213-005X
- Volume :
- 21
- Issue :
- 9
- Database :
- MEDLINE
- Journal :
- Enfermedades infecciosas y microbiologia clinica
- Publication Type :
- Academic Journal
- Accession number :
- 14572387
- Full Text :
- https://doi.org/10.1016/s0213-005x(03)72999-1