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[Study on effect of drug concentration of "Bushen huayu jiedu fang" drug serum on drug-resistance lung cancer cells with serum pharmacology].
- Source :
-
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials [Zhong Yao Cai] 2003 Apr; Vol. 26 (4), pp. 263-5. - Publication Year :
- 2003
-
Abstract
- To explore Rh123 ion concentration effect of "Bushen huayu jiedu fang" (BSHYJD) on drug-resistance lung cancer cells, tumor-bearing animal drug-serum pharmacology and flow cytometry method were utilitied. In contrast with normal animal drug serum, BSHYJD drug-serum of tumor-bearing animal would markedly increase Rh123 concentration in drug-resistance lung cancer cells(P < 0.05), but which hasn't marked discrepancy in contrast with normal animal drug-serum(P > 0.05), that indicated BSHYJD drug-serum has increased drug concentration in drug-resistance lung cancer cells.
- Subjects :
- Animals
Antineoplastic Agents pharmacology
Cisplatin pharmacology
Drug Combinations
Immune Sera biosynthesis
Lung Neoplasms metabolism
Lung Neoplasms pathology
Male
Mice
Neoplasm Transplantation
Rhodamine 123 metabolism
Tumor Cells, Cultured
Drug Resistance, Neoplasm drug effects
Drugs, Chinese Herbal pharmacology
Immune Sera pharmacology
Plants, Medicinal chemistry
Subjects
Details
- Language :
- Chinese
- ISSN :
- 1001-4454
- Volume :
- 26
- Issue :
- 4
- Database :
- MEDLINE
- Journal :
- Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials
- Publication Type :
- Academic Journal
- Accession number :
- 14528692