Photochemical ligation of DNA "words" for DNA computing.

Authors :: Kishi N
Ogino M
Saito I
Yoshimura Y
Fujimoto K
Source :: Nucleic acids research. Supplement (2001) [Nucleic Acids Res Suppl] 2003 (3), pp. 183-4.
Publication Year :: 2003
Abstract: The photochemical DNA computing of 5-vinyluracil ((V)U) containing oligodeoxynucleotides (ODNs) tethered multiple "DNA words" is demonstrated. A new MARK and UNMARK operation based on the (V)U mediated reversible DNA photoligation has been developed for multiple-word DNA computing. The utility of this operation for DNA computing is demonstrated by solving a small Satisfiability problem (SAT problem) in which information was encoded in three tandem words.