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Synthesis and hypnotic-sedative activities of N-substituted uracil on mice.
- Source :
-
Nucleic acids research. Supplement (2001) [Nucleic Acids Res Suppl] 2003 (3), pp. 25-6. - Publication Year :
- 2003
-
Abstract
- N3-Phenacyl-N1-substituted uracils 3a-q were synthesized by introduction of substituents at the N1-position of N3-phenacyluracil 2, and their hypnotic and sedative activities were evaluated. Pharmacological activities of these N3-phenacyl-N1-substituted uracils were examined using hypnotic activity and synergistic effects with pentobarbital or diazepam for the hypnotic and sedative activities.
Details
- Language :
- English
- Issue :
- 3
- Database :
- MEDLINE
- Journal :
- Nucleic acids research. Supplement (2001)
- Publication Type :
- Academic Journal
- Accession number :
- 14510362
- Full Text :
- https://doi.org/10.1093/nass/3.1.25