Back to Search
Start Over
Diffuse biliary tract injury after orthotopic liver transplantation.
- Source :
-
American journal of surgery [Am J Surg] 1992 Nov; Vol. 164 (5), pp. 536-40. - Publication Year :
- 1992
-
Abstract
- An unusual type of diffuse biliary tract injury after liver transplantation that is characterized by multiple intrahepatic biliary strictures, ductal dilatations, fluid collections, or intrahepatic abscesses has been identified. Over a 5-year period, a total of 10 patients (2%) developed diffuse intrahepatic biliary injury with established vascular patency and no obvious source for their biliary tract pathology. All patients received livers preserved in University of Wisconsin solution with a mean preservation time of 16 hours. This biliary tract injury was associated with the presence of severe preservation injury and Roux limb biliary reconstruction. Of the 10 patients, 5 were treated nonoperatively with multiple stricture dilations and stent placements, 3 underwent retransplantation, 1 was treated operatively with hepaticojejunostomy, and 1 died of sepsis. This study suggests that this complication appears to be related to preservation injury and that the etiology may be ischemic in origin.
- Subjects :
- Adenosine
Adolescent
Adult
Aged
Alanine Transaminase blood
Allopurinol
Aspartate Aminotransferases blood
Bile Duct Diseases etiology
Child
Child, Preschool
Cholangitis etiology
Follow-Up Studies
Glutathione
Graft Survival
Hepatic Artery
Humans
Hypertonic Solutions administration & dosage
Infant
Infant, Newborn
Insulin
Jaundice etiology
Liver physiopathology
Liver Transplantation physiology
Middle Aged
Organ Preservation
Raffinose
Reoperation
Retrospective Studies
Solutions administration & dosage
Thrombosis etiology
Biliary Tract Diseases etiology
Liver Transplantation adverse effects
Organ Preservation Solutions
Subjects
Details
- Language :
- English
- ISSN :
- 0002-9610
- Volume :
- 164
- Issue :
- 5
- Database :
- MEDLINE
- Journal :
- American journal of surgery
- Publication Type :
- Academic Journal
- Accession number :
- 1443384
- Full Text :
- https://doi.org/10.1016/s0002-9610(05)81196-1