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Abnormalities of chromosome 18 in myelodysplastic syndromes and secondary leukemia.

Authors :
Berger R
Le Coniat M
Derré J
Flexor MA
Hillion J
Source :
Cancer genetics and cytogenetics [Cancer Genet Cytogenet] 1992 Oct 15; Vol. 63 (2), pp. 97-9.
Publication Year :
1992

Abstract

Monosomy 18 and partial deletion of 18q are nonrandom events in myelodysplastic syndromes (MDS) and secondary acute myeloblastic leukemia (sAML). They are part of complex chromosome abnormalities, as shown in the present study of six patients with MDS and sAML. We compared occurrence of chromosome 18 abnormalities in these syndromes with that in de novo AML.

Details

Language :
English
ISSN :
0165-4608
Volume :
63
Issue :
2
Database :
MEDLINE
Journal :
Cancer genetics and cytogenetics
Publication Type :
Academic Journal
Accession number :
1423238
Full Text :
https://doi.org/10.1016/0165-4608(92)90387-n