Selective multiplication of dihydrofolate reductase genes in methotrexate-resistant variants of cultured murine cells. 1978.

Authors :: Alt FW
Kellems RE
Bertino JR
Schimke RT
Source :: Biotechnology (Reading, Mass.) [Biotechnology] 1992; Vol. 24, pp. 397-410.
Publication Year :: 1992

Subjects :: Animals
DNA Replication
Drug Resistance genetics
History, 20th Century
Mice
Tumor Cells, Cultured enzymology
Methotrexate pharmacology
Tetrahydrofolate Dehydrogenase genetics

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