Immunosuppression by whole-body irradiation and its effect on oedema in experimental cerebral ischaemia.

Authors :: Strachan RD
Kane PJ
Cook S
Chambers IR
Clayton CB
Mendelow AD
Source :: Acta neurologica Scandinavica [Acta Neurol Scand] 1992 Sep; Vol. 86 (3), pp. 256-9.
Publication Year :: 1992
Abstract: The effect of global immunosuppression by sublethal whole body X-irradiation on the development of cerebral oedema was assessed 24 h after right middle cerebral artery occlusion in the rat. Irradiation produced a significant leukopenia and thrombocytopaenia, and significantly reduced cortical oedema when compared to non-irradiated control animals.

Subjects :: Animals
Blood Platelets radiation effects
Brain immunology
Brain radiation effects
Leukocyte Count radiation effects
Male
Neutrophils radiation effects
Platelet Count radiation effects
Rats
Rats, Wistar
Specific Gravity
Blood Platelets immunology
Brain Edema immunology
Cerebral Infarction immunology
Immunosuppression Therapy
Neutrophils immunology
Radiation Injuries, Experimental immunology
Whole-Body Irradiation

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