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[Initial results of hybrid chemotherapy of Hodgkin's disease using COPP/VBA].
- Source :
-
Orvosi hetilap [Orv Hetil] 1992 Oct 25; Vol. 133 (43), pp. 2755-7. - Publication Year :
- 1992
-
Abstract
- 19 patients with advanced, previously untreated Hodgkin's disease were treated with COPP/ABV (cyclophosphamide, vincristine, procarbasine, prednisolone, adriamycin, bleomycine, vinblastine) hybrid regimen. Complete response was achieved in 8 patients, partial response in 9 patients and primary treatment failure occurred in 2 patients. Two patients received involved field irradiation for the residual disease. 17 months after finishing the therapy one of the complete responders suffered a relapse. Of the 8 partial responders, 5 patients relapsed. 2 relapses occurred during the treatment and 3 relapses were observed in the first 7 months of follow-up. 2 of the partial responders and both nonresponders succumbed to their disease. There were no serious side effects and treatment-related death did not occur.
- Subjects :
- Antineoplastic Combined Chemotherapy Protocols therapeutic use
Bleomycin therapeutic use
Cyclophosphamide therapeutic use
Doxorubicin therapeutic use
Hodgkin Disease pathology
Humans
Neoplasm Staging
Prednisone therapeutic use
Procarbazine therapeutic use
Prognosis
Vinblastine therapeutic use
Vincristine therapeutic use
Hodgkin Disease drug therapy
Subjects
Details
- Language :
- Hungarian
- ISSN :
- 0030-6002
- Volume :
- 133
- Issue :
- 43
- Database :
- MEDLINE
- Journal :
- Orvosi hetilap
- Publication Type :
- Academic Journal
- Accession number :
- 1383907