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Analysis of heart rate variability to assess hemodynamic alterations following induction of anesthesia.
- Source :
-
Journal of cardiothoracic and vascular anesthesia [J Cardiothorac Vasc Anesth] 1992 Dec; Vol. 6 (6), pp. 651-7. - Publication Year :
- 1992
-
Abstract
- Extensive changes in hemodynamics and cardiac rhythm during induction of anesthesia may be mediated by altered responses of the autonomic nervous system to anesthetic agents. Analysis of the power spectrum of the heart rate (PSHR) variability can supply information about the autonomic nervous system, and may be used in order to assess this phenomenon. In this study, 78 patients undergoing coronary artery bypass graft surgery were evaluated. Anesthesia was induced with sufentanil, and neuromuscular blockade with vecuronium, a combination that may cause a decrease in heart rate. Before and after induction of anesthesia, the heart rate (HR), blood pressure (BP), cardiac output (CO), cardiac index (CI), and PSHR components were recorded. PSHR was obtained by using a special algorithm and data acquisition system for real-time spectral analysis. A low-frequency component (LFa, mainly sympathetic) was analyzed from a band of 0.04 Hz to 0.1 Hz. A high-frequency component (RFa, parasympathetic) was identified by the respiratory frequency spectrum. Alterations of the heart rate after induction of anesthesia were defined in order to separate the patient population into two groups: slow heart rate (slow-HR) and stable heart rate (stable-HR). Slow heart rate was defined as a decrease in HR of more than 20% of the baseline value. The variables were analyzed and compared between the slow-HR (n = 25) and stable-HR (n = 53) groups in order to verify the possibility of identifying patients prone to hemodynamic changes after anesthesia induction. There were no differences in preoperative HR, BP, CO, or CI between groups before anesthesia induction.(ABSTRACT TRUNCATED AT 250 WORDS)
- Subjects :
- Adult
Aged
Autonomic Nervous System physiology
Blood Pressure drug effects
Blood Pressure physiology
Bradycardia physiopathology
Cardiac Output drug effects
Cardiac Output physiology
Central Venous Pressure drug effects
Central Venous Pressure physiology
Electrocardiography drug effects
Female
Heart Rate physiology
Hemodynamics physiology
Humans
Male
Middle Aged
Respiration drug effects
Respiration physiology
Stroke Volume drug effects
Stroke Volume physiology
Sufentanil administration & dosage
Vecuronium Bromide administration & dosage
Vecuronium Bromide pharmacology
Anesthesia, Intravenous
Autonomic Nervous System drug effects
Heart Rate drug effects
Hemodynamics drug effects
Sufentanil pharmacology
Subjects
Details
- Language :
- English
- ISSN :
- 1053-0770
- Volume :
- 6
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Journal of cardiothoracic and vascular anesthesia
- Publication Type :
- Academic Journal
- Accession number :
- 1361865
- Full Text :
- https://doi.org/10.1016/1053-0770(92)90045-9