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The treatment of hairy cell leukemia: an update.
- Source :
-
Leukemia [Leukemia] 1992; Vol. 6 Suppl 2, pp. 24-7. - Publication Year :
- 1992
-
Abstract
- The treatment of hairy cell leukemia (HCL) requires continuing update. The role for splenectomy is extremely limited. Alfa-interferon therapy has been available and utilized for five years; there have been few complete remissions. The experience with Pentostatin has resulted in a majority of clinical complete remissions after several months of therapy, but persistence of a small percentage of hairy cells in the bone marrow. The most recent therapeutic agent, 2-chloro-deoxyadenosine (2-CDA) is given for seven days and results in a complete remission in the great majority of patients with no evidence of persistent bone marrow disease. If this trend persists, 2-CDA will become first line therapy for HCL as it may cure the disease.
Details
- Language :
- English
- ISSN :
- 0887-6924
- Volume :
- 6 Suppl 2
- Database :
- MEDLINE
- Journal :
- Leukemia
- Publication Type :
- Academic Journal
- Accession number :
- 1349662