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[Paracoccidioides brasiliensis (Lutz, 1908) isolated by hemoculture in a patient with the acquired immunodeficiency syndrome (AIDS)].
- Source :
-
Revista do Instituto de Medicina Tropical de Sao Paulo [Rev Inst Med Trop Sao Paulo] 1992 Nov-Dec; Vol. 34 (6), pp. 565-7. - Publication Year :
- 1992
-
Abstract
- A case of an AIDS patient with positive blood culture for Paracoccidiodes brasiliensis is reported. The patient was a 29-years-old male born in Nova Londrina (Paraná State, Brazil) who presented splenomegaly and fever of unknown origin. Three blood cultures were performed, each one of them for aerobic bacteria, mycobacteria and fungi. Cultures for aerobic bacteria and mycobacteria were negative. However, the yeast phase P. brasiliensis was isolated from two cultures in BHI agar, 20 days after inoculation in Negroni medium. The patient was classified in group V according to the Centers for Disease Control (CDC) criteria for AIDS, due to a Pneumocystis carinii pneumonia. Treatment was discontinued due to an individual decision of the patient on the second dose of amphotericin B. This antibiotic was replaced by ketoconazole in the daily dose of 800 mg. The patient died one year after the isolation of P. brasiliensis on blood culture.
- Subjects :
- AIDS-Related Opportunistic Infections drug therapy
Adult
Amphotericin B administration & dosage
Fungemia drug therapy
Humans
Ketoconazole administration & dosage
Male
Paracoccidioidomycosis drug therapy
Treatment Refusal
AIDS-Related Opportunistic Infections microbiology
Fungemia microbiology
Paracoccidioides isolation & purification
Paracoccidioidomycosis microbiology
Subjects
Details
- Language :
- Portuguese
- ISSN :
- 0036-4665
- Volume :
- 34
- Issue :
- 6
- Database :
- MEDLINE
- Journal :
- Revista do Instituto de Medicina Tropical de Sao Paulo
- Publication Type :
- Academic Journal
- Accession number :
- 1342126