Massive haemorrhage from rupture of a pancreatic pseudocyst after pentamidine-associated pancreatitis.

A 40 year-old man with the acquired immunodeficiency syndrome who was treated with intravenous pentamidine suffered a massive spontaneous haemorrhage caused by rupture of a pancreatic pseudocyst after pentamidine-induced pancreatitis. The patient previously presented symptomatic hypoglycaemia, severe nephrotoxicity and hyperkalaemia, while not receiving any other drug but pentamidine. This is the first case reported of such a complication of pentamidine induced pancreatitis, and one of the few cases reported of the latter adverse event.